CIA agent and former U.S. Marine war veteran, James Silva, leads a Special Activities Division team code-named Overwatch to raid a Russian FSB safe house in the United States. Under the remote supervision of James Bishop and his team, the mission is to locate and destroy shipments of caesium before the highly radioactive substance can be weaponized. In the ensuing firefight, most of the Russians and Overwatch operative Greg Vickers are killed, but critical intelligence on the caesium is destroyed. Silva executes the last survivor, a teenager who warns him that he is making a mistake.

Sixteen months later, in the Southeast Asian country of Indocarr, police officer Li Noor surrenders himself at the US Embassy to negotiate for passage out of the country in exchange for information. Noor is revealed to be the asset of Overwatch agent Alice Kerr and reveals he possesses a disc containing information on the caesium, and is able to negotiate passage out of the country in exchange for unlocking the disc, which is programmed to self destruct within eight hours. Ambassador Dorothy Brady is visited by the country's Deputy Foreign Minister and state intelligence agent Axel, with the two demanding that Noor be handed over as he is wanted for espionage. Meanwhile, Noor fends off an assassination attempt by disguised government agents in the embassy infirmary using his skills as a former member of the elite tactical squad.

Wanting access to the intel, Silva's team is instructed to take Noor to an airplane at an airstrip 22 miles away, being provided with remote assistance from Bishop's team in Colombia. En route they are attacked by a group of men on motorcycles, who use a brief camera blackout to plant a bomb on one of the vehicles. During the ensuing gunfight, operative Sam Snow is mortally injured, and sacrifices herself to buy the group time. Taking cover in a restaurant, they are again attacked by Axel's men, in which Silva is saved by Noor and operative William

https://en.wikipedia.org/wiki/Mile_22
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